Gene

nop2

ID

ZDB-GENE-050309-7

Name

NOP2 nucleolar protein homolog (yeast)

Symbol

nop2 Nomenclature History

Previous Names

cb164 (1)
im:6893299 (1)
sb:cb164
si:dkey-91i17.1

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have rRNA (cytosine-C5-)-methyltransferase activity. Predicted to be involved in maturation of LSU-rRNA and rRNA base methylation. Predicted to localize to nucleolus. Is expressed in several structures, including digestive system; mesoderm; nervous system; neural tube; and pectoral fin. Orthologous to human NOP2 (NOP2 nucleolar protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

12 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb164 (9 images)
IMAGE:6893299 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nop2 Human Ortholog

No data available

Associated With nop2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018314	RsmB/NOL1/NOP2-like, conserved site
Domain	IPR001678	SAM-dependent methyltransferase RsmB-F/NOP2-type domain
Domain	IPR011023	Nop2p
Domain	IPR049560	SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core
Family	IPR023267	RNA (C5-cytosine) methyltransferase
Family	IPR023273	RNA (C5-cytosine) methyltransferase, NOP2
Homologous_superfamily	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily